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Journal of Exercise Nutrition & Biochemistry 2002;6(3):197-204.
Articles : Effects of Squalene Supplementation on Antioxidative Capacity and Blood Profiles
qualene is an unsaturated hydrocarbon consisted of 20 carbons and 50 hydrogens with six double-bonds. It is widely distributed in human bodies, animals, and plants. Especially, deep sea sharks contain large amount of squalene in its liver. There are research reports that squalene has following physiochemical functions as antioxidants, detoxication, increase the immunity anti-cancerous, reduction of choleserol, and cell regencration. There is a great demand for safe and multi-functional ergogenic aids in the market. Among many candidates, squalene is a quite promising substance as an ergogenic aid satisfying all these requirements. The subjects of experiment were 13 students of K university and they were divided into squalene group (n=7) and placebo group (n=6). Ten mg of squalene had been dosed per day for four weeks and graded exercise test to the max had been conducted to observe the changes achieved in each group after taking squalene. Results were as follows: 1) A significant increase in HDL was found after the supplementation of squalene. 2) There was no significant change in blood index (RBC, WBC, Hct, Hb) before and after the intake of squalene and exercise. 3) The intake of squalene significantly reduced resting level of MDA. From these results, squalene may have some antioxidative effects for using as an ergogenic aid.
Key Words: squalene, antioxidant, ergogenic aid, blood profile


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