Articles : Effect of Green-tea Polyphenol and Vitamin Complex on Antioxidative Enzyme Activity during Exercise in Rats

Journal of Exercise Nutrition & Biochemistry 2002;6(3):285-290.

Abstract

Exercise increases the generation of oxygen free radical an lipid peroxidation. Polyphenol and vitamin C, E are known to prevent lipid peroxidation during exercise. Among the known polyphenol, the polyphenol extracted from Green tea as used has the similar effect of antioxidant. Therefore we examined the effects of polyphenol or vitamin complex(vitamin C+E) on antioxidants enzymes activities in rat (N=40). All rats were exercise training on the treadmill for 6weeks (25 m/sec for 1hour). They were administered 5% of polyphenol and 50㎎ of vitamin C+E before the exercise, during whole period of the experiment. Administration group (PA: polyphenol administration, VA; vitamin complex administration, PVA; polyphenol & vitmin complex administration) and theother group was administered the same amount of water at the same time point (CON). Oneway ANOVA was performed as the statistical analysis. This study analyzed whether oxidative stress could be relieved by taking polypheonl, non-enzymatic antioxidant and vitamin C and E complex during long running exercise. Long-term polyphenol administration made SOD increase in liver and the activation of SOD is higher in red muscle than in white muscle in gastrocnemius. Furthemore it;s imporatant to verifty the mechanism of antioxidase by non-enzymatic antioxidant about oxidative injury in case of exercise at the maximun as well as check the effect of antioxidant by the activity of GPX or catalase.

Key Words: vitamin complex, oxidative stress, antioxidant enzyme, polyphenol, 비타민복합체, 산화스트레스, 항산화효소, 폴리페놀