Articles : Influence of Angiotensin Converting Enzyme Gene Polymorphism on Physical Fitness in Response to Combined Training in Male Students

Journal of Exercise Nutrition & Biochemistry 2003;7(2):119-126.

Abstract

The purpose of this study was to investigate the influence of angiotensin converting enzyme gene polymorphism on physical fitness to combined training of male students. The research population consisted of 40 middle school boy (Ⅱ type-14, ID type=13, DD type=13). Subjects participated in 12 weeks of combined both aerobic and resistance training to five times per week for 40-50minutes. The ACE polymorphism was genotyped by PCR amplication of the 64, 86 and 490bq alleles. The results of this study were as following; 1. Muscle endurance was shown a case of increasing in all ACE genotype after 6 weeks, but after 12 weeks only Ⅱ genotype had been increased as significant difference. Also, muscle endurance was significantly higher in Ⅱ genotype than in DD genotype after 12 weeks. 2. Power was shown a case of increasing in all ACE genotype after 6 weeks, but after 12 weeks only DD genotype had been increased as significant difference. And, power was significantly higher in DD genotype than in Ⅱ genotype after 12 weeks, 3. Muscle strength, agility, flexibility and balance were shown tendency of increasing in all ACE gene after 6 weeks of combined training, but there was no significant difference. These data suggest that physical fitness response to combined training may be affected by ACE genotype.

Key Words: Combined training, ACE gene polymorphism, Physical fitness