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Journal of Exercise Nutrition & Biochemistry 2009;13(4):243-249.
The Effects of 24 Week Training and Detraining on Cardiac Autonomic Nervous System Activity and Antioxidant Enzyme Gene Expression in Obese Children
Abstract
The purpose of this study was to examine the effect of 24 week training and detraining on cardiac autonomic nervous system activity and antioxidant enzyme gene expression in obese children. We studied 16 boys with obesity and 19 age-matched normal weight controls during the 24 weeks of aerobic exercise training and 12 weeks of detraining. Measurements included body weight, % fat, BMI, TP, VLF, LF, GPX and SOD gene expressions. The results showed that there were differences in baseline TP, VLF, and LF between CO and obese group (p < .05). In TR and DT, the baseline VLF was lower than 12 and 24 week (p < .05). There were differences in baseline levels of GPX gene expression between CO and obese, while those of SOD were no differences between groups. After 24 weeks, the training-induced GPX and SOD gene expressions were increased. However, those did not change by detraining. In conclusion, these data suggested that aerobic exercise training over 12 weeks enhanced VLF and antioxidant gene expression in obese children, in addition we recommended cardiac autonomic nerve active and antioxidant gene expressions tend to maintain during 12 weeks detraining periods.
Key Words: obese children, detraining, autonomic nervous system, antioxidant enzymeobese children, detraining, autonomic nervous system, antioxidant enzyme


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