Modern workplaces have transitioned from active to sedentary, resulting in prolonged periods of sitting. One reason for this shift is the change from paper-based to electronic and paperless work [1]. The nature of work in developing countries has changed drastically, and the focus has shifted to a more sedentary nature rather than being mobile [2]. Current occupations require the heavy use of computers (due to prolonged sitting), which may contribute to poor health function3. Professionals currently spend a substantial portion of their working hours seated in front of computers, leading to restricted mobility and potential systemic health issues [4]. Most of an individual’s work hours are invested in immobility, resulting in dysfunction of the cardiovascular and musculoskeletal systems [3,5].

Epidemiological investigations involving over 200,000 individuals have revealed prolonged sitting as a major concern for all-cause mortality, contributing to 7% of premature deaths. In 2018, approximately 25% of all jobs in the United States involved prolonged sitting, a significant increase from 15% in 1960 [1]. Forty-two percentage male and forty-seven percentage of females spend an average of 6.3 hours in sedentary and seated roles during their 8-hour shifts [6].

Prolonged sitting can alter the normal curvature of the spine, exerting increased pressure on intervertebral discs and resulting in anterior compression and posterior stretching. This can cause rearward movement of the nucleus pulposus, potentially leading to disc herniation. Changes in thoracic compliance induce a three-dimensional alteration in the form and movement of the thoracic wall during respiration, impacted by the foremost and back enunciations of the thoracic spine and rib cage [7]. Biomechanical changes in postural arrangement influence the scopes of movement, area, and coupling pattern of enunciations between thoracic spinal vertebrae and the rib confine, affecting lung compliance by altering articular development during respiration [8].

Body position significantly influences respiratory function, with changes affecting the length and tension generation of respiratory muscles, specifically the diaphragm. Compared to a typical upright posture, a flump, poor posture significantly impacts pulmonary functions, expiratory flow, and lumbar lordosis [9]. Evidence indicates that even minor changes in posture can alter respiration, with flump sitting reducing tidal volume, forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and peak expiratory flow rate (PEFR) compared with that during upright postures [10].

Additionally, pulmonary function is influenced by factors such as age, weight, height, and race, with lung capacity and elasticity decreasing with age. This leads to decreased lung function, making respiration more challenging and increasing the risk of getting pulmonary conditions such as “chronic obstructive pulmonary disease (COPD)”. Aging can also change the structure of airways and lung tissues, narrowing airways and reducing flexibility, further impeding airflow. The walls of the air sacs in the lungs may also become thicker and less efficient at exchanging oxygen and carbon dioxide. These age-related changes in lung structure and function contribute to symptoms such as shortness of breath, decreased exercise tolerance, and increased susceptibility to respiratory infections. Therefore, keeping a healthy lifestyle, including customary activity and abstaining from smoking, is crucial to mitigate the effects of aging on lung health [11].

Our findings revealed significant changes in the lung function of the participants. Post-hoc testing revealed significant differences in FVC, FEV1, FEV1/FVC, and PEFR for 2-4 h, 4-6 h, and > 6 h of sitting (Table 2).

We evaluated changes in lung function during prolonged sitting. The finding of this study indicated a noteworthy change in pulmonary function when an individual was seated for a longer period. These results revealed that changes in lung function occur during sitting.

Our findings revealed a decrease in lung function during inspiration among participants seated for extended periods, consistent with those of various literature reports biomechanical changes, such as muscle stiffness and change in torso ROM, due to prolonged sitting [12,13]. The adoption of a posture that flexes the spine, for example, when one sits on a PC and accomplishes work area work, has become undeniable in many workspaces. During slumping, the lumbar region and pelvic spinal portions are subject to inactive designs to keep up with the situation against gravity [14,15]. Consequently, flexed spine posture can cause stiffness & decrease muscle versatility. Similarly, Beach et al. revealed that lumbar spine constraint increases with prolonged sitting. A diminished range of lumbar movement after prolonged sitting has been previously reported [12,15]. Callaghan and McGill revealed a diminished range of motion in the lumbar region which is incited by structures like lumbar flexors that provide passive resistance.

Moreover, weakness in the deep flexor and extensor muscles of the neck may destabilize the cervical and thoracic spine, affecting rib cage biomechanics and altering inspiratory muscle function by modifying curves of force length and capabilities of force-production [16,17].

Additionally, respiratory dysfunction may result from changes in force-length bends, muscle imbalances, and segmental unsteadiness of the cervical spine. Segmental unsteadiness in the cervical spine might reach out to the thoracic spine on account of specific muscles, for example, the longus colli, which append to regions impacted by neck proprioceptor impedance, in this manner confounding ideal spinal arrangement [18]. Moreover, sagittal stances of the thoracic spine were seen to be related to forward head pose, cervical versatility, and neck torment [19]. Concerning respiratory capability, thoracic kyphosis was demonstrated to be joined by dyspnea and ventilator brokenness [20]. In healthy young individuals with normally positioned diaphragms, a slumped sitting posture increases intra-abdominal pressure by bringing the ribs closer to the pelvis, hindering diaphragmatic descent during inspiration [21].

Our study highlights a decline in lung function during prolonged sitting. Despite its limitation of a small sample size, we anticipate that our findings will serve as a reference for future studies investigating the effects of prolonged sitting.